Treatments for Blood Clots and Microclots

Updated October 30, 2026

No treatment has been shown in randomized trials to clear fibrin amyloid microclots or improve Long COVID or post-vaccine symptoms as of October 2026. The approaches below are being studied, at very different stages, and each card says how far the evidence has got.

Large clots are differentA deep vein thrombosis, pulmonary embolism or stroke is an emergency with established hospital treatment. Sudden chest pain, breathlessness, a swollen painful leg or stroke symptoms need emergency care now.
Lab research

Nattokinase and lumbrokinase

Nattokinase broke down lab-made microclots in one 2024 preprint, but didn't significantly shrink plasma-derived microclots in a 2026 study. No study has measured microclots in people taking it.

Read the research review on amyloid-test.com
Early, uncontrolled data

Plasmapheresis and DFPP

Double filtration plasmapheresis filters large molecules such as fibrinogen and antibodies out of plasma, in courses of 2 to 4 weeks at Edogawa Hospital in Tokyo. Groups in Tokyo, Dresden and Berlin report improvements, but the data are early and mostly uncontrolled.

Read the research review on amyloid-test.com
One uncontrolled cohort

Triple anticoagulant therapy

Triple therapy combines clopidogrel, aspirin and apixaban. The only published data come from an uncontrolled cohort of 91 patients, there are no randomized trials, and the combination carries real bleeding risk.

Read the research review on amyloid-test.com

Every one of these carries trade-offs, and several raise bleeding risk, so any plan belongs with a clinician who can monitor you.